The first half belonged to the Panthers, as they built a commanding 21-point lead. Running back Dion Lewis spearheaded the offensive charge, finding the end zone twice, while quarterback Bill Stull connected with wide receiver Jonathan Baldwin for another touchdown. However, the Bearcats, led by the explosive Mardy Gilyard, refused to back down. Gilyard unleashed a spectacular performance, racking up 374 yards and two touchdowns as Cincinnati clawed their way back into the game.

With just over a minute remaining, Lewis's third rushing touchdown put the Panthers ahead 44-38. But a crucial mistake on the extra-point attempt, a muffed snap, kept the door open for the Bearcats. Cincinnati capitalized on the opportunity, as quarterback Tony Pike found Armon Binns for a 29-yard touchdown pass with 33 seconds left, securing a thrilling 45-44 victory. This unforgettable game, later ranked 127th on ESPN's list of the Greatest College Games, is a testament to the unpredictable nature of college football and the power of perseverance.