The St Louis Rams selected Jerome as their first round pick, and 10th overall in the 1993 NFL Draft. In just his first season as a Pro, Bettis received Rookie of the Year honors as he was second in yardage in the League that year and third in total yards from scrimmage per ProFootballHOF.com.

A few years later, he was famously traded to the Pittsburgh Steelers, where he remained for the balance of his 13-year career. He led the Rams in rushing in three seasons and the Steelers in 8. When he retired, he had amassed 13662 yards rushing, which at the time listed him as the fifth-highest total in NFL history.

He was an All-Pro in several seasons and played in 6 Pro Bowl games. Jerome Bettis was selected for enshrinement into the Pro Football Hall of Fame in 2015’s class of inductees.