On October 25, 1964, during a game against the San Francisco 49ers, the Minnesota Vikings were leading 27-17 in the fourth quarter. With just over two minutes remaining, 49ers quarterback John Brodie fumbled the ball after being sacked by Vikings defensive end Carl Eller.

Vikings linebacker Dave Whitsell recovered the fumble at the San Francisco 49ers' 20-yard line. However, teammate Jim Marshall, a defensive end, mistakenly picked up the loose ball and started running the wrong way. He ran 66 yards down the field, unaware that he was heading into his own end zone.

The confusion on the field was palpable. Some Vikings players yelled at Marshall to stop, but he thought they were encouraging him to run for a touchdown. San Francisco 49ers players were initially unsure of what was happening but then realized the opportunity and tackled Marshall in his own end zone, resulting in a safety for the 49ers.

The safety cut the Vikings' lead to 27-19, but they ultimately won the game 27-22. Despite the win, Marshall's blunder became one of the most famous and embarrassing plays in NFL history. He was initially ridiculed for his mistake, but later gained respect for his sportsmanship and humility.