His size allowed him to destroy the blocks and defenses of opposing lines where it was said he would typically take out two to three players at a time. With his outstanding athleticism and the genius of Walter Camp, he also is credited with introducing the "pulling guard" play. The All- America selections originated in 1889 by Walter Camp, and Pudge was on this initial team. He repeated in 1890-91, his last two seasons at Yale. Yale was a significant football power during that era, and Pudge helped lead the Bulldog team to undefeated seasons in 1888 and 1891 and one-loss seasons during the 1889 and 1890 campaigns.

The 1888 team amazingly outscored their opponents 698-0 that season! The National Football Foundation welcomed the collegiate career of Pudge Heffelfinger into the College Football Hall of Fame in 1951. As great of a collegiate player as Pudge was, that's not exactly what Pudge is best known for, though. After college Heffelfinger continued playing for independent teams, and on November 12, 1892, the Allegheny Athletic Association near Pittsburgh paid Pudge Heffelfinger the tidy sum of $500 to play just one game with them against their heated rivals, the Pittsburgh Athletic Club. The AAA with Pudge did win the game that day by the score of 4-0, according to the Pro Football Hall of Fame.